In 1945, Sister Teresa Patricia, S.N.D., College President, announced the organization of the Emmanuel College Building Fund under the chairmanship of Archbishop Richard Cushing. The immediate objective of the fund is to $800,000 for the construction of a new Science Building. In his own inimitable way, Archbishop Cushing gave the project the first push by promising to pledge $100,000 to be paid in yearly installment of $20,000 for five years, if each alumna would pledge $100 to be paid in yearly installment of $20. The building was designed by Charles Maginnis and construction began in May 1947. This helped focus the efforts of the alumnae association towards a single goal and helped developed plans for Marian Hall and the Library Building.

 

It was the first construction project on campus since the opening of the Administration Building in 1916. Its creation was necessary for the college to receive accreditation from the American Association of University Women which was achieved in June 1954. When the structure opened in 1949, the Physics Department was located on the first floor, the Biology Department was located on the second floor and the Chemistry Department was located on the third floor. In 1971, under the leadership of Sr. Mary Camilla Coveney, chairman of the Biology Department, developed a media room, known as Room 3D, where films and slides could be shown. It was also a place where students could study and talk. In 1985, use of Alumnae Hall by the College ceased, and it was rent to neighborhood businesses and hospitals.